What is the tolerance margin used by the EPA to enhance safety?

The tolerance margin used by the EPA to enhance safety is set at 100 times. This means that when evaluating potential risks associated with exposure to pesticides, the EPA establishes tolerances that are significantly lower than levels that could potentially cause harm. By implementing this 100-fold safety margin, the EPA aims to protect sensitive populations, including children, the elderly, and those with chronic health issues, ensuring that even the most vulnerable groups are safeguarded.

This approach reflects the EPA's commitment to precautionary measures in health risk assessments. The use of multiple safety factors serves to address uncertainties and variability in human exposure and sensitivity to chemicals. Thus, while the agency may rely on scientific data to determine permissible levels of substances, applying a 100 times safety factor accounts for the possibility of misestimating risks associated with long-term exposure or potential synergistic effects with other chemicals.